Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684566 | 1.00 | CYP11B1 (0.40) | CYP11B1CYP11B2LMNAMAPK1TRPA1 | |
| SCHEMBL312750 | 0.85 | CYP11B1 (0.43) | CYP11B1CYP11B2LMNAMAPK1ALDH1A1 | |
| SCHEMBL8687555 | 0.84 | CYP11B1 (0.42) | CYP11B1CYP11B2LMNAMAPK1ALDH1A1 | |
| SCHEMBL26704592 | 0.81 | KDM4E (0.44) | CYP11B1CYP11B2LMNAALDH1A1ENPP2 | |
| SCHEMBL6714982 | 0.80 | RAB9A (0.42) | CYP11B1CYP11B2LMNAENPP2SIRT2 | |
| SCHEMBL6714980 | 0.80 | RAB9A (0.42) | CYP11B1CYP11B2LMNAENPP2SIRT2 | |
| SCHEMBL4686324 | 0.80 | CYP11B1 (0.36) | CYP11B1CYP11B2ENPP2SIRT2 | |
| SCHEMBL19808692 | 0.79 | ENPP2 (0.39) | CYP11B1CYP11B2LMNAMAPK1TRPA1 | |
| SCHEMBL4022652 | 0.79 | CYP11B1 (0.43) | CYP11B1CYP11B2LMNAMAPK1ALDH1A1 | |
| SCHEMBL4695995 | 0.77 | ENPP2 (0.35) | CYP11B1CYP11B2ENPP2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492392-B1 | INHIBITING TUMOR CELL PROLIFERATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| US-6355665-B1 | ANTIHISTAMINES, ANTIALLERGENS AND IRRITABLE BOWEL SYNDROME. | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-03-12 | — | — | US | disclosed |