Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28176782 | 0.96 | MAPT (0.42) | MAPTTSHR | |
| Hydrochloric Acid SCHEMBL2229191 | 0.89 | MAPT (0.34) | MAPTTSHR | |
| SCHEMBL28204342 | 0.83 | MAPT (0.31) | MAPT | |
| SCHEMBL12469758 | 0.83 | ALDH1A1 (0.39) | — | |
| SCHEMBL12220163 | 0.82 | — | — | |
| SCHEMBL12220188 | 0.82 | — | — | |
| SCHEMBL12220182 | 0.82 | — | — | |
| SCHEMBL12220208 | 0.82 | — | — | |
| SCHEMBL12220168 | 0.80 | — | — | |
| SCHEMBL9942137 | 0.78 | MAPT (0.40) | MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |