Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 4/20 | 0.47 |
| ▸ | TK1 | P04183 | 5/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | TK2 | O00142 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547404 | 1.00 | RNASE1 (0.49) | RNASE1TOP2ATK1ABCG2ABCB1 | |
| SCHEMBL9547415 | 0.86 | POLB (0.55) | RNASE1TK1 | |
| SCHEMBL9547412 | 0.86 | POLB (0.55) | RNASE1TK1 | |
| SCHEMBL16494725 | 0.84 | RNASE1 (0.64) | RNASE1TOP2ATK1ABCG2ABCB1 | |
| SCHEMBL735094 | 0.84 | TOP2A (0.53) | RNASE1TOP2ATK1ABCG2ABCB1 | |
| SCHEMBL734481 | 0.83 | TOP2A (0.51) | RNASE1TOP2ATK1ABCG2ABCB1 | |
| SCHEMBL735281 | 0.82 | RNASE1 (0.55) | RNASE1TOP2ATK1ABCG2ABCB1 | |
| SCHEMBL24059082 | 0.82 | TOP2A (0.55) | RNASE1TOP2ATK1 | |
| SCHEMBL21563908 | 0.82 | TOP2A (0.65) | RNASE1TOP2ATK1 | |
| SCHEMBL1514947 | 0.82 | TOP2A (0.65) | RNASE1TOP2ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218102-A | Easily synthesized, hybridize well with target sequences | IMPROBIO (BE) | 1993-06-08 | — | — | US | disclosed |