Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TK1 | P04183 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547415 | 1.00 | POLB (0.55) | POLBTK1BCHETYMSRNASE1 | |
| SCHEMBL9547404 | 0.86 | RNASE1 (0.49) | TK1RNASE1 | |
| SCHEMBL9547401 | 0.86 | RNASE1 (0.49) | TK1RNASE1 | |
| SCHEMBL15216188 | 0.82 | POLB (0.64) | POLBTK1TYMS | |
| SCHEMBL263768 | 0.82 | POLB (0.64) | POLBTK1TYMS | |
| SCHEMBL263767 | 0.82 | POLB (0.64) | POLBTK1TYMS | |
| SCHEMBL3694340 | 0.82 | POLB (0.64) | POLBTK1BCHE | |
| SCHEMBL5040039 | 0.82 | TYMS (0.60) | POLBTK1TYMSRNASE1 | |
| SCHEMBL2584183 | 0.82 | TYMS (0.60) | POLBTK1TYMSRNASE1 | |
| SCHEMBL4731694 | 0.81 | RNASE1 (0.67) | POLBTK1BCHERNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218102-A | Easily synthesized, hybridize well with target sequences | IMPROBIO (BE) | 1993-06-08 | — | — | US | disclosed |