Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659890 | 0.98 | L3MBTL1 (0.67) | L3MBTL1TDP1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL1545294 | 0.92 | L3MBTL1 (0.63) | L3MBTL1TDP1ALDH1A1HSD17B10SMN1; SMN2 | |
| Water SCHEMBL10556855 | 0.90 | L3MBTL1 (0.61) | L3MBTL1TDP1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL29742239 | 0.89 | L3MBTL1 (0.77) | L3MBTL1TDP1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11090671 | 0.89 | KDM4E (0.50) | L3MBTL1TDP1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL4427769 | 0.88 | L3MBTL1 (0.59) | L3MBTL1TDP1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL30960112 | 0.88 | L3MBTL1 (0.59) | L3MBTL1TDP1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11091669 | 0.87 | KDM4E (0.52) | L3MBTL1TDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29742293 | 0.85 | L3MBTL1 (0.70) | L3MBTL1TDP1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11022671 | 0.85 | SMN1; SMN2 (0.50) | L3MBTL1TDP1ALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246965-A | Leukotriene antagonist | CIBA-GEIGY (US) | 1993-09-21 | — | — | US | disclosed |