SCHEMBL9547503

SCHEMBL9547503

O=C(Nc1ccc2ccccc2c1)Nc1ccc2ccccc2c1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.89
NPC1 O15118 5/20 0.89
MAPT P10636 3/20 0.89
CA2 P00918 2/20 0.70
MEN1 O00255 5/20 0.67
KMT2A Q03164 5/20 0.67
POLB P06746 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
CA12 O43570 1/20 0.66
CA1 P00915 1/20 0.66
CA9 Q16790 1/20 0.66
ALDH1A1 P00352 2/20 0.62
CYP1A2 P05177 2/20 0.62
KDM4E B2RXH2 1/20 0.62
CYP2C19 P33261 1/20 0.62
HIF1A Q16665 1/20 0.62
HTT P42858 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
KDR P35968 1/20 0.62
GRIK1 P39086 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049543 0.94 MAPT (1.00) RAB9ANPC1MAPTCA2MEN1
SCHEMBL30697002 0.94 MAPT (1.00) RAB9ANPC1MAPTCA2MEN1
SCHEMBL24272500 0.91 MAPT (0.80) RAB9ANPC1MAPTCA2MEN1
SCHEMBL24272501 0.91 MAPT (0.80) RAB9ANPC1MAPTCA2MEN1
SCHEMBL14470404 0.89 NPC1 (0.77) RAB9ANPC1MAPTCA2MEN1
SCHEMBL11057371 0.89 NPC1 (0.77) RAB9ANPC1MAPTCA2MEN1
SCHEMBL8325083 0.88 RAB9A (0.71) RAB9ANPC1MAPTCA2MEN1
SCHEMBL8596702 0.88 RAB9A (0.71) RAB9ANPC1MAPTCA2MEN1
SCHEMBL22588930 0.88 MAPT (0.75) RAB9ANPC1MAPTCA2MEN1
SCHEMBL14470417 0.86 RAB9A (0.73) RAB9ANPC1MAPTCA2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5194660-A Processes for producing carbamates and isocyanates UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-03-16 US disclosed
US-4816070-A PRINTED CIRCUITS, ADHESION TECHO INSTRUMENTS INVESTMENTS LTD. (IL) 1989-03-28 US disclosed
US-4715894-A AMINIMIZATION OF SMEAR TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) 1987-12-29 US disclosed
US-4657632-A CONTAINING A THIOUREA AND A UREA COMPOUND TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) 1987-04-14 US disclosed
EP-0216531-A1 Use of immersion tin and tin alloys as a bonding medium for multilayer circuits TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) 1987-04-01 EP disclosed
US-4622400-A SULFONATION, ALKALI FUSION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-11-11 US disclosed