Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542868 | 0.90 | EPHX2 (0.51) | EPHX2KDM4EPOLBSIGMAR1EPHX1 | |
| SCHEMBL9544427 | 0.80 | EPHX2 (0.51) | EPHX2KDM4EPOLBEPHX1KMT2A | |
| SCHEMBL22096239 | 0.80 | EPHX2 (0.51) | EPHX2KDM4EPOLBEPHX1KMT2A | |
| SCHEMBL4662750 | 0.80 | EPHX2 (0.51) | EPHX2KDM4EPOLBEPHX1KMT2A | |
| SCHEMBL560936 | 0.79 | EPHX2 (0.53) | EPHX2SIGMAR1EPHX1SMN1; SMN2CYP1A2 | |
| SCHEMBL2907816 | 0.78 | HPGD (0.53) | EPHX2MEN1MAPTKMT2AATM | |
| SCHEMBL9130829 | 0.78 | HPGD (0.53) | EPHX2MEN1MAPTKMT2AATM | |
| SCHEMBL2810358 | 0.78 | EPHX2 (0.49) | EPHX2KDM4EPOLBEPHX1KMT2A | |
| SCHEMBL25129712 | 0.78 | SIGMAR1 (0.41) | KDM4EPOLBSIGMAR1EPHX1SMN1; SMN2 | |
| SCHEMBL27672250 | 0.77 | EPHX2 (0.53) | EPHX2SIGMAR1EPHX1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |