Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547644 | 1.00 | POLB (0.51) | POLBELANEMAPTALDH1A1PKM | |
| SCHEMBL9547645 | 0.79 | POLB (0.47) | POLBELANEMAPTALDH1A1PKM | |
| SCHEMBL28883352 | 0.71 | POLB (0.70) | POLBELANEMAPTALDH1A1PKM | |
| SCHEMBL12009061 | 0.69 | TCF4 (0.64) | POLBMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL18545496 | 0.69 | TCF4 (0.64) | POLBMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL8815712 | 0.69 | POLB (1.00) | POLBELANEMAPTALDH1A1PKM | |
| SCHEMBL28883409 | 0.67 | POLB (0.70) | POLBELANEMAPTALDH1A1PKM | |
| SCHEMBL15101837 | 0.67 | FNTA (0.46) | POLBELANEMAPTALDH1A1PKM | |
| SCHEMBL30285929 | 0.67 | POLB (0.63) | POLBELANEMAPTALDH1A1PKM | |
| SCHEMBL8990319 | 0.67 | POLB (0.63) | POLBELANEMAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236941-A | Hypoglycemic agents, diabetes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-08-17 | — | — | US | disclosed |