Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547641 | 0.79 | POLB (0.51) | POLBELANEMAPTALDH1A1HSD17B10 | |
| SCHEMBL9547644 | 0.79 | POLB (0.51) | POLBELANEMAPTALDH1A1HSD17B10 | |
| SCHEMBL28883352 | 0.67 | POLB (0.70) | POLBELANEMAPTALDH1A1HSD17B10 | |
| SCHEMBL30285929 | 0.67 | POLB (0.63) | POLBELANEMAPTALDH1A1HSD17B10 | |
| SCHEMBL18770820 | 0.67 | POLB (0.63) | POLBELANEMAPTALDH1A1HSD17B10 | |
| SCHEMBL8990319 | 0.67 | POLB (0.63) | POLBELANEMAPTALDH1A1HSD17B10 | |
| SCHEMBL11826902 | 0.67 | POLB (0.63) | POLBELANEMAPTALDH1A1HSD17B10 | |
| SCHEMBL152339 | 0.67 | TLR9 (0.64) | POLBELANEMAPTALDH1A1HSD17B10 | |
| SCHEMBL29386767 | 0.67 | TLR9 (0.64) | POLBELANEMAPTALDH1A1HSD17B10 | |
| SCHEMBL6032649 | 0.66 | POLB (0.53) | POLBELANEMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236941-A | Hypoglycemic agents, diabetes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-08-17 | — | — | US | disclosed |