Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385749 | 0.81 | ALDH1A1 (0.62) | TSPONPC1ALDH1A1HTTRAB9A | |
| SCHEMBL6110886 | 0.81 | ALDH1A1 (0.50) | ACHENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6112331 | 0.81 | POLB (0.51) | ACHEALDH1A1HTTPDK1 | |
| SCHEMBL27605169 | 0.81 | ALDH1A1 (0.44) | NPC1ALDH1A1RAB9AGLASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27540694 | 0.80 | NPC1 (0.61) | TSPONPC1ALDH1A1HTTRAB9A | |
| SCHEMBL27323388 | 0.78 | NPC1 (0.50) | TSPONPC1ALDH1A1HTTRAB9A | |
| SCHEMBL3053571 | 0.77 | MAPK14 (0.63) | PTGESALOX5ACHENPC1ALDH1A1 | |
| SCHEMBL27499854 | 0.77 | PDK1 (0.43) | ACHETSPONPC1ALDH1A1HTT | |
| SCHEMBL7695802 | 0.76 | MAPK14 (0.53) | PTGESALOX5NPC1ALDH1A1HTT | |
| SCHEMBL2162478 | 0.75 | ROCK1 (0.53) | NPC1ALDH1A1HTTRAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194660-A | Processes for producing carbamates and isocyanates | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-03-16 | — | — | US | disclosed |
| US-4621149-A | PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-11-04 | — | — | US | disclosed |