SCHEMBL9547650

SCHEMBL9547650

Cc1ccc(N(C(=O)N(c2ccc(C)cc2)c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.56
ALDH1A1 P00352 7/20 0.48
TSHR P16473 1/20 0.48
LMNA P02545 2/20 0.46
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
TRPM8 Q7Z2W7 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 2/20 0.42
TDP1 Q9NUW8 3/20 0.42
ACHE P22303 1/20 0.42
PKM P14618 2/20 0.41
HTT P42858 2/20 0.41
ATM Q13315 2/20 0.41
HPGD P15428 1/20 0.41
NLRP1 Q9C000 1/20 0.41
GAA P10253 1/20 0.41
MEN1 O00255 1/20 0.41
NTSR1 P30989 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5933542 0.82 ALDH1A1 (0.48) NPSR1ALDH1A1TSHRLMNACES2
SCHEMBL5933533 0.82 ALDH1A1 (0.46) NPSR1ALDH1A1TSHRLMNACES2
SCHEMBL10669577 0.81 NPSR1 (0.59) NPSR1ALDH1A1TSHRCES2CES1
SCHEMBL5933685 0.80 ALDH1A1 (0.44) NPSR1ALDH1A1TSHRLMNACES2
SCHEMBL5933681 0.80 ALDH1A1 (0.44) NPSR1ALDH1A1TSHRLMNACES2
SCHEMBL16026954 0.80 ALDH1A1 (0.44) NPSR1ALDH1A1TSHRLMNACES2
SCHEMBL1954828 0.80 ALOX5 (0.47) NPSR1ALDH1A1TSHRLMNACES2
SCHEMBL21551502 0.78 ALDH1A1 (0.44) NPSR1ALDH1A1TSHRLMNACES2
SCHEMBL10670734 0.78 CHRM5 (0.42) NPSR1ALDH1A1TSHRLMNASMN1; SMN2
SCHEMBL7026676 0.78 NPSR1 (0.36) NPSR1ALDH1A1TSHRLMNACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5194660-A Processes for producing carbamates and isocyanates UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-03-16 US disclosed
EP-0083096-B1 PRODUCTION OF URETHANE COMPOUNDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-02-25 EP disclosed
US-4621149-A PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-11-04 US disclosed
US-4400329-A Process for the manufacture of thiochlorformates SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1983-08-23 US disclosed
EP-0083096-A2 Production of urethane compounds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-07-06 EP disclosed