Ethylene

Ethylene

SCHEMBL9547669

C=C.C=C.C=C.C=C.CCC=CC1CC(=O)NC1=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CRBN Q96SW2 1/20 0.33
NPC1 O15118 1/20 0.33
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288297 0.96 MAP3K14 (0.38) MAP3K14KDM4EALDH1A1GAAMAPT
SCHEMBL6685314 0.95 MAP3K14 (0.36) MAP3K14KDM4EALDH1A1GAAMAPT
Boric Acid SCHEMBL9438359 0.90 KDM4E (0.33) MAP3K14KDM4EALDH1A1GAAMAPT
SCHEMBL5134781 0.82 LMNA (0.31) ALDH1A1NPC1
SCHEMBL11606967 0.77 ALDH1A1 (0.41) ALDH1A1NPC1
SCHEMBL5545836 0.77 ALDH1A1 (0.41) ALDH1A1NPC1
SCHEMBL2720057 0.77 ALDH1A1 (0.41) ALDH1A1NPC1
SCHEMBL5617257 0.77 ALDH1A1 (0.41) ALDH1A1NPC1
SCHEMBL1060200 0.77 ALDH1A1 (0.41) ALDH1A1NPC1
SCHEMBL11120922 0.77 ALDH1A1 (0.41) ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5240628-A Adsorbing n-polyalkylenepolyamine-substituted alkenylsuccinimide onto fine particles of ferrites, distilling off water and solvent and dispersing particles in a base oil NOK CORPORATION (JP) 1993-08-31 US disclosed