Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthraquinone SCHEMBL3654040 | 0.84 | SLC7A5 (0.60) | SLC7A5MEN1LMNAKMT2APKM | |
| Anthraquinone SCHEMBL27983859 | 0.84 | SLC7A5 (0.60) | SLC7A5MEN1LMNAKMT2APKM | |
| SCHEMBL4800950 | 0.80 | MEN1 (0.50) | SMN1; SMN2MEN1LMNAKMT2ATP53 | |
| Phentydrone SCHEMBL31505070 | 0.78 | SLC7A5 (0.44) | SLC7A5MEN1LMNAKMT2APKM | |
| Valine SCHEMBL4263389 | 0.76 | MAOB (0.46) | SLC7A5SMN1; SMN2MEN1LMNAKMT2A | |
| Phthalic Anhydride SCHEMBL8525072 | 0.76 | SLC7A5 (0.54) | SLC7A5SMN1; SMN2MEN1LMNAKMT2A | |
| Valine SCHEMBL11524576 | 0.75 | SLC7A5 (0.62) | SLC7A5SMN1; SMN2MEN1KMT2APKM | |
| Valine SCHEMBL6639200 | 0.75 | SLC7A5 (0.62) | SLC7A5MEN1KMT2APKMNPC1 | |
| Phthalimide SCHEMBL2319609 | 0.74 | GSK3B (0.52) | SLC7A5SMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL9267507 | 0.74 | APAF1 (0.43) | HSP90AA1HSP90AB1SMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180841-A | PREPARATION OF 1-AMINO-2-CHLORO-4-HYDROXYANTHRAQUINONE | BASF AKTIENGESELLSCHAFT (DE) | 1993-01-19 | — | — | US | disclosed |