Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | SDCBP | O00560 | 1/20 | 0.38 |
| ▸ | SDC2 | P34741 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10595556 | 0.80 | MAOB (0.59) | MAOBCYP2A6MAOACES1SRD5A1 | |
| Anthraquinone SCHEMBL27983859 | 0.80 | SLC7A5 (0.60) | SLC7A5LMNAMEN1KMT2APKM | |
| Anthraquinone SCHEMBL3654040 | 0.80 | SLC7A5 (0.60) | SLC7A5LMNAMEN1KMT2APKM | |
| Valine SCHEMBL10425187 | 0.79 | SLC7A5 (0.54) | SLC7A5MEN1CYP2D6CYP2C19KMT2A | |
| Methylamine SCHEMBL27578982 | 0.78 | MAOA (0.65) | MAOBCYP2A6MAOACES1SRD5A1 | |
| Benzene SCHEMBL28357254 | 0.78 | MAOB (0.71) | MAOBCYP2A6MAOACES1SRD5A1 | |
| SCHEMBL1268680 | 0.76 | MAOA (0.74) | MAOBCYP2A6MAOACES1SRD5A1 | |
| SCHEMBL29353311 | 0.76 | MAOA (0.74) | MAOBCYP2A6MAOACES1SRD5A1 | |
| SCHEMBL24746 | 0.76 | MAOA (0.74) | MAOBCYP2A6MAOACES1SRD5A1 | |
| Valine SCHEMBL9547786 | 0.76 | SLC7A5 (0.46) | SLC7A5AKR1B1TP53SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074375-B1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INT (DE) | 2018-04-04 | — | — | EP | disclosed |
| EP-2855419-B1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARB OXYLIC ACIDS | BOEHRINGER INGELHEIM INT (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-3074375-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | Boehringer Ingelheim International GmbH (DE) | 2016-10-05 | — | — | EP | disclosed |
| US-9308194-B2 | Indanyloxyphenylcyclopropanecarboxylic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| WO-2015078802-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-06-04 | — | — | WO | disclosed |
| US-20150148347-A1 | INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-05-28 | — | — | US | disclosed |
| EP-2855419-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARB OXYLIC ACIDS | Boehringer Ingelheim International GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| US-8633182-B2 | Indanyloxyphenylcyclopropanecarboxylic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| WO-2013178575-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARB OXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-05 | — | — | WO | disclosed |
| US-20130324514-A1 | INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-05 | — | — | US | disclosed |
| WO-2009053443-A2 | INDANE COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2009-04-30 | — | — | WO | disclosed |
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130324514-A1 | INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | GPR119, GPR65, INSR | MAOB 3777/4885CYP2A6 824/4885MAOA 4023/4885 |
| US-20150148347-A1 | INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | GPR119, INSR, GPR65 | MAOB 3872/4885CYP2A6 993/4885MAOA 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.