SCHEMBL9547808

SCHEMBL9547808

CCCCCOC(C)c1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.49
LTA4H P09960 2/20 0.46
ESR1 P03372 4/20 0.41
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP2C19 P33261 1/20 0.41
NR1H2 P55055 1/20 0.41
RNASEL Q05823 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
UGCG Q16739 4/20 0.41
GBA2 Q9HCG7 4/20 0.41
GBA1 P04062 3/20 0.41
LCT P09848 3/20 0.41
MGAM O43451 2/20 0.41
SI P14410 2/20 0.41
RARB P10826 3/20 0.41
HSD17B3 P37058 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547799 0.98 NR5A1 (0.51) NR5A1LTA4HESR1LMNAUGCG
SCHEMBL9547831 0.98 NR5A1 (0.51) NR5A1LTA4HESR1LMNAUGCG
SCHEMBL9547755 0.93 NR5A1 (0.56) NR5A1LTA4HESR1LMNACYP1A2
SCHEMBL9547785 0.93 NR5A1 (0.56) NR5A1LTA4HESR1LMNACYP1A2
SCHEMBL9761610 0.93 NR5A1 (0.56) NR5A1LTA4HESR1LMNACYP1A2
SCHEMBL9547839 0.88 ESR1 (0.42) LTA4HESR1LMNACYP1A2CYP2D6
SCHEMBL9547860 0.83 ESR1 (0.47) NR5A1LTA4HESR1LMNACYP1A2
SCHEMBL9331239 0.82 RARB (0.65) TSHRRARBALDH1A1TP53
SCHEMBL9330512 0.82 RARB (0.65) TSHRRARBALDH1A1TP53
SCHEMBL9328575 0.82 RARB (0.65) TSHRRARBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0288297-B1 OPTICALLY ACTIVE BENZENE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
US-4985590-A Optically active benzene derivatives and process for preparation thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-15 US disclosed