Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547755 | 1.00 | NR5A1 (0.56) | NR5A1LTA4HESR1ADRA2AADORA3 | |
| SCHEMBL9547785 | 1.00 | NR5A1 (0.56) | NR5A1LTA4HESR1ADRA2AADORA3 | |
| SCHEMBL9547799 | 0.95 | NR5A1 (0.51) | NR5A1LTA4HESR1ADRA2AADORA3 | |
| SCHEMBL9547831 | 0.95 | NR5A1 (0.51) | NR5A1LTA4HESR1ADRA2AADORA3 | |
| SCHEMBL9547808 | 0.93 | NR5A1 (0.49) | NR5A1LTA4HESR1ADRA2AADORA3 | |
| SCHEMBL9547860 | 0.85 | ESR1 (0.47) | NR5A1LTA4HESR1ADORA3SLC6A2 | |
| SCHEMBL9126557 | 0.85 | NR5A1 (0.47) | NR5A1LTA4HHSD17B10CNR2 | |
| SCHEMBL9761558 | 0.84 | ESR1 (0.41) | NR5A1LTA4HESR1ADORA3SLC6A2 | |
| SCHEMBL9761562 | 0.84 | ESR1 (0.41) | NR5A1LTA4HESR1ADORA3SLC6A2 | |
| SCHEMBL11213967 | 0.82 | NPC1 (0.46) | LTA4HLMNAALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297745-B1 | OPTICALLY ACTIVE ETHER DERIVATIVES, PREPARATION PROCESSES THEREFOR, LIQUID CRYSTAL MATERIALS AND AN OPTICAL SWITCHING ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-5013479-A | Aromatic ether esters containing two or three benzene rings | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0297745-A1 | Optically active ether derivatives, preparation processes therefor, liquid crystal materials and an optical switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-01-04 | — | — | EP | disclosed |