SCHEMBL9547865

SCHEMBL9547865

CCC(C)C(=O)OC(C)c1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.46
OPRM1 P35372 4/20 0.46
LMNA P02545 2/20 0.46
CHRM1 P11229 2/20 0.46
SLC6A2 P23975 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP1A2 P05177 1/20 0.46
PGR P06401 1/20 0.46
CHRM2 P08172 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
AR P10275 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
DRD1 P21728 1/20 0.46
TBXA2R P21731 1/20 0.46
PTGS1 P23219 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547863 1.00 ESR1 (0.46) ESR1OPRM1LMNACHRM1SLC6A2
SCHEMBL14258829 0.93 HCAR2 (0.40) ESR1LMNATDP1MAPTALDH1A1
SCHEMBL2740694 0.86 ACHE (0.41) LMNATDP1CYP1A2CYP3A4CYP2D6
SCHEMBL28265857 0.85 KLK7 (0.40) LMNATDP1CYP1A2MAPTCYP2C9
SCHEMBL13704203 0.85 ALDH1A1 (0.43) LMNATDP1CYP1A2CYP2D6MAPT
SCHEMBL872787 0.84 HCAR2 (0.51) LMNACHRM1CYP1A2CHRM2CYP2D6
SCHEMBL9329235 0.83 MAPT (0.50) MAPTCA1CA2ALDH1A1TSHR
SCHEMBL9329240 0.83 MAPT (0.50) MAPTCA1CA2ALDH1A1TSHR
SCHEMBL2740617 0.83 AKR1C3 (0.43) TDP1MAPTPTGS1HSD17B10ALDH1A1
SCHEMBL2740659 0.82 MAPT (0.50) CYP1A2MAPTCYP2C9CYP2C19PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0288297-B1 OPTICALLY ACTIVE BENZENE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
US-4985590-A Optically active benzene derivatives and process for preparation thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-15 US disclosed
EP-0288297-A2 Optically active benzene derivatives and process for preparation thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-10-26 EP disclosed