Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503405 | 0.71 | KDM4E (1.00) | KDM4ELMNAMAPTMEN1ALOX15 | |
| SCHEMBL95164 | 0.71 | KDM4E (1.00) | KDM4ELMNAMAPTMEN1ALOX15 | |
| SCHEMBL9548052 | 0.71 | KDM4E (0.55) | KDM4ELMNAMAPTMEN1ALOX15 | |
| SCHEMBL13234140 | 0.71 | KDM4E (0.55) | KDM4ELMNAMAPTMEN1ALOX15 | |
| SCHEMBL1007130 | 0.69 | ALDH1A1 (0.73) | KDM4ELMNAMAPTMEN1ALOX15 | |
| SCHEMBL2257837 | 0.68 | KDM4E (0.52) | KDM4ELMNAMAPTMEN1ALOX15 | |
| SCHEMBL3323518 | 0.68 | GAA (1.00) | KDM4ELMNAMAPTMEN1ALOX15 | |
| SCHEMBL4045529 | 0.67 | TSHR (0.61) | KDM4ELMNAMAPTMEN1ALOX15 | |
| SCHEMBL9139821 | 0.67 | ALDH1A1 (1.00) | KDM4ELMNAMAPTMEN1ALOX15 | |
| SCHEMBL11008658 | 0.66 | ALDH1A1 (0.62) | KDM4ELMNAMAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217971-A | Anticoagulants, hypotensive agents, antiallergens and antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0377457-A1 | Thiazole compounds, processes for the preparation thereof, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |