Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.60 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30790364 | 1.00 | PDCD1 (0.60) | PDCD1CD274DPP4NR4A2KMT2A | |
| SCHEMBL19923153 | 0.87 | PDCD1 (0.47) | PDCD1CD274DPP4NR4A2PDK2 | |
| SCHEMBL13824010 | 0.86 | NR4A2 (0.48) | PDCD1CD274NR4A2PDK2PTPN5 | |
| SCHEMBL18621557 | 0.85 | PDCD1 (0.44) | PDCD1CD274NR4A2LMNAPDK2 | |
| SCHEMBL23078658 | 0.83 | HSD17B1 (0.44) | PDCD1CD274NR4A2 | |
| SCHEMBL30609912 | 0.82 | NR4A2 (0.43) | PDCD1CD274NR4A2PDK2PTPN5 | |
| SCHEMBL13726819 | 0.82 | NR4A2 (0.43) | PDCD1CD274NR4A2PDK2PTPN5 | |
| SCHEMBL28210679 | 0.82 | MKNK1 (0.49) | PDCD1CD274NR4A2ALDH1A1PDK2 | |
| SCHEMBL10981274 | 0.82 | DPP4 (0.45) | PDCD1CD274DPP4KMT2AFOLH1 | |
| SCHEMBL11571880 | 0.81 | SUCNR1 (0.53) | PDCD1CD274KMT2AFOLH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5194293-A | — | — | None | — | — | JP | disclosed |
| WO-2021043116-A1 | BIPHENYL COMPOUNDS, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国药科大学 | 2021-03-11 | — | — | WO | disclosed |
| EP-3636637-A1 | INHIBITING FATTY ACID SYNTHASE (FASN) | Forma Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| WO-2012150221-A2 | NOVEL HALOGENATED BENZYL ALCOHOL ESTERS OF CYCLOPROPANE CARBOXYLIC ACID AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012150208-A1 | USE OF SUBSTITUTED BENZYL ALCOHOL ESTERS OF CYCLOPROPANECARBOXYLIC ACID FOR CONTROLLING INSECTICIDE-RESISTANT INSECTS | BAYER CROPSCIENCE AG (DE) | 2012-11-08 | — | — | WO | disclosed |
| JP-H05194293-A | PREPARATION OF TERTIARY TRI-AND TETRAFLUOROPHENYLBENZYL ALCOHOLS | MERCK PATENT GMBH | 1993-08-03 | — | — | JP | disclosed |