Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19920886 | 0.92 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL19920888 | 0.90 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL29174009 | 0.90 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL3689280 | 0.89 | — | — | |
| SCHEMBL9548171 | 0.89 | — | — | |
| SCHEMBL141406 | 0.88 | CA12 (0.42) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| Ethane SCHEMBL452807 | 0.85 | CA12 (0.40) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| Methane SCHEMBL6661669 | 0.85 | CA12 (0.40) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| Propane SCHEMBL6655388 | 0.85 | CA12 (0.40) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL321886 | 0.85 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290426-B1 | 2-CYANOETHYL-CONTAINING ORGANOXYSILANE COMPOUND, SILSESQUIOXANE, AND MAKING METHODS | SHINETSU CHEMICAL CO (JP) | 2021-11-17 | — | — | EP | disclosed |
| US-20180066112-A1 | 2-CYANOETHYL-CONTAINING ORGANOXYSILANE COMPOUND, SILSESQUIOXANE, AND MAKING METHODS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-03-08 | — | — | US | disclosed |
| EP-3290426-A1 | 2-CYANOETHYL-CONTAINING ORGANOXYSILANE COMPOUND, SILSESQUIOXANE, AND MAKING METHODS | Shin-Etsu Chemical Co., Ltd. (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-5240630-A | Refrigeration compositions containing diester-amides of dialkanolamines | ETHYL CORPORATION (US) | 1993-08-31 | — | — | US | disclosed |