Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | VHL | P40337 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL27360866 | 0.83 | NOTUM (0.37) | EPHX2ALDH1A1LMNAVHLS1PR1 | |
| SCHEMBL27348675 | 0.81 | NOTUM (0.40) | EPHX2ALDH1A1LMNAVHLRAB9A | |
| SCHEMBL9548280 | 0.81 | NOTUM (0.40) | EPHX2ALDH1A1LMNAVHLRAB9A | |
| SCHEMBL9548269 | 0.76 | POLB (0.49) | EPHX2LMNARAB9AHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9548357 | 0.72 | LMNA (0.47) | ALDH1A1LMNA | |
| SCHEMBL9548380 | 0.72 | SMN1; SMN2 (0.46) | EPHX2LMNARAB9ASMN1; SMN2ATM | |
| SCHEMBL18099930 | 0.70 | SMN1; SMN2 (0.34) | ALDH1A1LMNARAB9AHPGDSMN1; SMN2 | |
| SCHEMBL9548297 | 0.69 | PPARA (0.52) | EPHX2ALDH1A1LMNAS1PR1S1PR3 | |
| SCHEMBL9232450 | 0.69 | ALDH1A1 (0.40) | ALDH1A1LMNAACHEMAPK1 | |
| SCHEMBL6402508 | 0.67 | EPHX2 (0.46) | EPHX2ALDH1A1LMNAS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273989-A | 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | claimed |
| CN-1055537-A | 3, two replacement-2-different azoles alkane of 5-and different azoles, its preparation method contain the preparation and the application thereof of this composition | HOECHST AG (DE) | 1991-10-23 | — | — | CN | claimed |
| US-5273989-A | 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| CN-1055537-A | 3, two replacement-2-different azoles alkane of 5-and different azoles, its preparation method contain the preparation and the application thereof of this composition | HOECHST AG (DE) | 1991-10-23 | — | — | CN | disclosed |