Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548582 | 0.83 | TSHR (0.32) | LMNATSHR | |
| SCHEMBL9548577 | 0.81 | TSHR (0.31) | TSHR | |
| SCHEMBL10895703 | 0.79 | ALDH1A1 (0.40) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28006761 | 0.78 | LMNA (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28077865 | 0.71 | — | — | |
| SCHEMBL9548592 | 0.71 | — | — | |
| SCHEMBL8712167 | 0.70 | LMNA (0.40) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL16499942 | 0.69 | LMNA (0.43) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL225621 | 0.69 | LMNA (0.48) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10481065 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194103-A | Plasticizers in plastic bonded explosives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-03-16 | — | — | US | disclosed |