Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.37 |
| ▸ | GMPS | P49915 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.36 |
| ▸ | PI4KA | P42356 | 3/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548690 | 0.91 | ADORA2A (0.42) | ADORA3ADORA2ASLC28A1GMPSTAS1R3 | |
| SCHEMBL9548638 | 0.88 | ADORA2A (0.39) | ADORA3ADORA2ASLC28A1GMPSTAS1R3 | |
| SCHEMBL9548762 | 0.85 | ADORA3 (0.40) | ADORA3CYP3A4NFKB1BLMSMN1; SMN2 | |
| SCHEMBL9548802 | 0.84 | ADORA2A (0.42) | ADORA3ADORA2ASLC28A1GMPSTAS1R3 | |
| SCHEMBL9548707 | 0.82 | ADORA3 (0.41) | ADORA3ADORA2ASLC28A1GMPSTAS1R3 | |
| SCHEMBL9548884 | 0.79 | — | — | |
| SCHEMBL9548745 | 0.79 | ADORA2A (0.40) | ADORA3ADORA2ASLC28A1GMPSTAS1R3 | |
| SCHEMBL9548683 | 0.76 | TAS1R3 (0.35) | ADORA3ADORA2ASLC28A1GMPSTAS1R3 | |
| SCHEMBL9548774 | 0.76 | — | — | |
| SCHEMBL9548775 | 0.76 | ADORA3 (0.44) | ADORA3CYP3A4NFKB1BLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |