SCHEMBL9548813

SCHEMBL9548813

C[SiH](C)[C@]1(n2ccc(N)nc2=O)C[C@H](OC(C)(C)C)[C@@](C=O)(CO)O1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDE3A Q14432 3/20 0.32
PDE4D Q08499 1/20 0.32
SLC29A1 Q99808 1/20 0.32
CACNA1F O60840 2/20 0.31
LMNA P02545 2/20 0.31
ALB P02768 2/20 0.31
MAPT P10636 2/20 0.31
CACNA1D Q01668 2/20 0.31
CACNA1S Q13698 2/20 0.31
CACNA1C Q13936 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9548697 0.90 PDE4D (0.31) PDE3APDE4DSLC29A1
SCHEMBL9548846 0.87 PDE3A (0.32) PDE3APDE4DSLC29A1CACNA1FLMNA
SCHEMBL9548594 0.87 PDE3A (0.32) PDE3APDE4DSLC29A1CACNA1FLMNA
SCHEMBL9548735 0.84 PDE3A (0.32) PDE3APDE4DSLC29A1CACNA1FLMNA
SCHEMBL9548654 0.81 DUT (0.31)
SCHEMBL9548884 0.81
SCHEMBL9548751 0.79 ADORA3 (0.40) LMNA
SCHEMBL9548732 0.77
SCHEMBL9548883 0.76 PDE3A (0.38) PDE3APDE4DSLC29A1CACNA1FLMNA
SCHEMBL9548787 0.72 DUT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5192749-A Viricide, AIDS SYNTEX (U.S.A.) INC. (US) 1993-03-09 US disclosed