Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TK2 | O00142 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548818 | 1.00 | TK1 (0.38) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL28168107 | 0.87 | TK1 (0.39) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8931958 | 0.75 | TYMP (0.38) | TK1TK2 | |
| SCHEMBL28641784 | 0.75 | TK1 (0.41) | TK1LMNAALBBLMRNASE1 | |
| SCHEMBL4581987 | 0.74 | TK1 (0.40) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL29508780 | 0.74 | TK1 (0.38) | TK1ALDH1A1LMNAALBBLM | |
| SCHEMBL9062998 | 0.73 | RNASE1 (0.40) | TK1ALDH1A1RNASE1NPSR1TK2 | |
| SCHEMBL14388593 | 0.73 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL27436150 | 0.73 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL24059196 | 0.72 | RNASE1 (0.62) | TK1LMNAALBBLMRNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |