Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.40 |
| ▸ | TK1 | P04183 | 6/20 | 0.38 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548870 | 1.00 | TOP2A (0.40) | TOP2ATK1NT5M | |
| SCHEMBL3317625 | 0.92 | TK1 (0.41) | TOP2ATK1 | |
| SCHEMBL3317630 | 0.92 | TK1 (0.41) | TOP2ATK1 | |
| SCHEMBL9548669 | 0.85 | DUT (0.38) | — | |
| SCHEMBL9548678 | 0.85 | DUT (0.38) | — | |
| SCHEMBL9548647 | 0.84 | TK1 (0.45) | TK1NT5M | |
| SCHEMBL9548644 | 0.84 | TK1 (0.45) | TK1NT5M | |
| SCHEMBL1417674 | 0.81 | TK1 (0.45) | TOP2ATK1 | |
| SCHEMBL1417676 | 0.81 | TK1 (0.45) | TOP2ATK1 | |
| SCHEMBL1417610 | 0.81 | TK1 (0.45) | TOP2ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |