Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958950 | 0.77 | TTR (0.38) | TTR | |
| SCHEMBL2369945 | 0.75 | — | — | |
| SCHEMBL30057251 | 0.72 | ALDH1A1 (0.38) | TTR | |
| SCHEMBL7543636 | 0.68 | — | — | |
| SCHEMBL12302293 | 0.66 | TTR (0.44) | TTR | |
| SCHEMBL797108 | 0.65 | — | — | |
| SCHEMBL8443312 | 0.64 | ERN1 (0.47) | — | |
| SCHEMBL8006517 | 0.64 | TTR (0.41) | TTR | |
| SCHEMBL606643 | 0.64 | SELL (0.52) | TTR | |
| SCHEMBL324636 | 0.63 | PIM1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185450-A | Tetrazolium compounds for cell viability assays | UNIVERSITY OF SOUTH FLORIDA (US) | 1993-02-09 | — | — | US | disclosed |