⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797108 | 0.79 | — | — | |
| SCHEMBL9548920 | 0.75 | TTR (0.32) | — | |
| SCHEMBL839170 | 0.73 | — | — | |
| SCHEMBL9579632 | 0.63 | ALDH1A1 (0.32) | — | |
| SCHEMBL7837636 | 0.63 | — | — | |
| SCHEMBL29367291 | 0.62 | CYP1A2 (0.32) | — | |
| SCHEMBL561949 | 0.62 | PIM1 (0.33) | — | |
| SCHEMBL2250516 | 0.62 | CA12 (0.34) | — | |
| SCHEMBL21527922 | 0.62 | — | — | |
| SCHEMBL8634190 | 0.62 | PIM1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968618-A2 | IMAGEABLE EMBOLIC MICROSPHERE | Dreher, Matthew R. (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014152488-A2 | IMAGEABLE EMBOLIC MICROSPHERE | DREHER MATTHEW R (US) | 2014-09-25 | — | — | WO | claimed |
| CN-115137870-B | Emulsion comprising particles | 生物相容性英国公司 | 2024-05-10 | — | — | CN | disclosed |
| US-20230285601-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2023-09-14 | — | — | US | disclosed |
| US-11672876-B2 | Imageable embolic microsphere | BIOCOMPATIBLES UK LIMITED (GB) | 2023-06-13 | — | — | US | disclosed |
| CN-115137870-A | Emulsions comprising particles | 生物相容性英国公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114805644-B | Nontransmissive polymer and preparation method and application thereof | 苏州美创医疗科技有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114805644-A | Nontransmissive polymer and preparation method and application thereof | 苏州美创医疗科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| US-11383008-B2 | Surface-modified polymeric substrates grafted with a properties-imparting compound using clip chemistry | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-07-12 | — | — | US | disclosed |
| CN-108883189-B | Emulsion comprising particles | 生物相容性英国公司 | 2022-06-21 | — | — | CN | disclosed |
| EP-3131897-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-2968618-A2 | IMAGEABLE EMBOLIC MICROSPHERE | Dreher, Matthew R. (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20150335779-A1 | Method of Embolization using a Radiopaque, Non-Biodegradable, Water-Insoluble Iodinated Benzyl Ether of PolyI(Vinyl Alcohol) | ANTIA THERAPEUTICS S.A. (CH) | 2015-11-26 | — | — | US | disclosed |
| WO-2015160634-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015160636-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | WO | disclosed |
| US-9115230-B2 | Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof | ANTIA THERAPEUTICS S.A. (CH) | 2015-08-25 | — | — | US | disclosed |
| WO-2014152488-A2 | IMAGEABLE EMBOLIC MICROSPHERE | DREHER MATTHEW R (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20130108574-A1 | RADIOPAQUE, NON-BIODEGRADABLE, WATER-INSOLUBLE IODINATED BENZYL ETHERS OF POLY(VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF | MERIT MEDICAL SYSTEMS, INC. | 2013-05-02 | — | — | US | disclosed |
| EP-2545085-A1 | RADIOPAQUE, NON- BIODEGRADABLE, WATER - INSOLUBLE IODINATED BENZYL ETHERS OF POLY (VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF | Universite Claude Bernard Lyon 1 (UCBL) (FR) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011110589-A1 | RADIOPAQUE, NON- BIODEGRADABLE, WATER - INSOLUBLE IODINATED BENZYL ETHERS OF POLY (VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF | UNIVERSITÉ CLAUDE BERNARD LYON 1 (UCBL) (FR) | 2011-09-15 | — | — | WO | disclosed |