Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22154931 | 0.81 | TAAR1 (0.52) | KIF11TSHRNPC1RAB9ATP53 | |
| SCHEMBL29080708 | 0.79 | KIF11 (0.49) | KIF11TSHRCYP19A1ALDH1A1MAPK1 | |
| SCHEMBL11862867 | 0.79 | KIF11 (0.49) | KIF11TSHRCYP19A1ALDH1A1MAPK1 | |
| SCHEMBL30791489 | 0.79 | KIF11 (0.49) | KIF11TSHRCYP19A1ALDH1A1NPC1 | |
| SCHEMBL29048828 | 0.79 | KIF11 (0.49) | KIF11TSHRCYP19A1ALDH1A1MAPK1 | |
| SCHEMBL34403 | 0.79 | KIF11 (0.49) | KIF11TSHRCYP19A1ALDH1A1NPC1 | |
| SCHEMBL78619 | 0.78 | HDAC4 (0.47) | KIF11TSHRCYP19A1ALDH1A1NPSR1 | |
| SCHEMBL29441583 | 0.78 | HDAC4 (0.47) | KIF11TSHRCYP19A1ALDH1A1NPSR1 | |
| SCHEMBL30791490 | 0.77 | CYP19A1 (0.62) | KIF11TSHRCYP19A1MAPK1NPSR1 | |
| SCHEMBL2394054 | 0.77 | CYP19A1 (0.62) | KIF11TSHRCYP19A1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290583-B1 | $g(a) OLIGONUCLEOTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1993-04-07 | — | — | EP | disclosed |
| EP-0290583-A1 | -g(a) OLIGONUCLEOTIDES. | CENTRE NAT RECH SCIENT (FR) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988004301-A1 | alpha OLIGONUCLEOTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1988-06-16 | — | — | WO | disclosed |