Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9549206 | 1.00 | FAAH (0.42) | FAAHGAAKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9549323 | 1.00 | FAAH (0.42) | FAAHGAAKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9549510 | 1.00 | FAAH (0.42) | FAAHGAAKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9067351 | 1.00 | FAAH (0.42) | FAAHGAAKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9549305 | 1.00 | FAAH (0.42) | FAAHGAAKDM4EALDH1A1HPGD | |
| SCHEMBL9549652 | 0.99 | FAAH (0.43) | FAAHGAAKDM4EALDH1A1HPGD | |
| SCHEMBL9549259 | 0.99 | FAAH (0.43) | FAAHGAAKDM4EALDH1A1HPGD | |
| SCHEMBL9549107 | 0.99 | FAAH (0.43) | FAAHGAAKDM4EALDH1A1HPGD | |
| Bromide SCHEMBL10392977 | 0.98 | FAAH (0.42) | FAAHGAAKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9549050 | 0.94 | GAA (0.41) | FAAHGAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288515-B1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | ISP INVESTMENTS INC. (US) | 1993-05-05 | — | — | EP | claimed |
| EP-0288515-A4 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | — | 1990-09-26 | — | — | EP | claimed |
| US-4837013-A | VISCOSITY ENHANCING AND HAIR CONDITIONING PROPERTIES | GAF CORPORATION (US) | 1989-06-06 | — | — | US | claimed |
| EP-0288515-A1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS. | GAF CORP (US) | 1988-11-02 | — | — | EP | claimed |
| WO-1988002985-A1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | GAF CORPORATION (US) | 1988-05-05 | — | — | WO | claimed |
| EP-0288515-B1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | ISP INVESTMENTS INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| EP-0288515-A4 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | — | 1990-09-26 | — | — | EP | disclosed |
| US-4837013-A | VISCOSITY ENHANCING AND HAIR CONDITIONING PROPERTIES | GAF CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0288515-A1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS. | GAF CORP (US) | 1988-11-02 | — | — | EP | disclosed |
| WO-1988002985-A1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | GAF CORPORATION (US) | 1988-05-05 | — | — | WO | disclosed |