SCHEMBL9549140

SCHEMBL9549140

CCCCCC1CCC(c2ccc(C(C)=O)cc2)CC1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.61
MAPT P10636 3/20 0.58
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
MAPK1 P28482 1/20 0.51
ESR2 Q92731 2/20 0.43
SPHK1 Q9NYA1 5/20 0.41
RAB9A P51151 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10341942 1.00 CYP2C9 (0.61) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL7661308 0.96 CYP2C9 (0.57) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10766628 0.96 CYP2C9 (0.57) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10766638 0.96 CYP2C9 (0.57) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10766643 0.96 CYP2C9 (0.57) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL7661304 0.96 CYP2C9 (0.57) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL9501207 0.95 CYP2C9 (0.62) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL19870479 0.95 CYP2C9 (0.62) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10763490 0.95 CYP2C9 (0.56) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10763487 0.95 CYP2C9 (0.56) CYP2C9MAPTALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4686757-A1 INHIBITORS OF EXPRESSION AND/OR FUNCTION e-therapeutics PLC (GB) 2026-02-04 EP disclosed
CN-116535303-B Method for synthesizing 4- (4-alkyl cyclohexyl) aryl ketone by replacing dichloroethane with methylcyclohexane 山东齐阳光电科技有限公司 2023-09-05 CN disclosed
CN-116535303-A Method for synthesizing 4- (4-alkyl cyclohexyl) aryl ketone by replacing dichloroethane with methylcyclohexane 山东齐阳光电科技有限公司 2023-08-04 CN disclosed
US-20150337013-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS MERCK SHARP & DOHME CORP. (US) 2015-11-26 US disclosed
US-20140073558-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CUBIST PHARMACEUTICALS, INC. (US) 2014-03-13 US disclosed
US-8507647-B2 Antibacterial agents for the treatment of gram positive infections CUBIST PHARMACEUTICALS, INC. (US) 2013-08-13 US disclosed
EP-1762605-B1 Naphthalene compound with terminal hydrogen, liquid crystal composition including the compound, and LCD device including the liquid crystal composition CHISSO PETROCHEMICAL CORP (JP) 2010-10-13 EP disclosed
US-5188759-A HALOACETYLENE DERIVATIVES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-02-23 US disclosed
EP-0149238-B1 NITROGEN CONTAINING HETEROCYCLES MERCK PATENT GmbH (DE) 1990-02-28 EP disclosed
US-4726911-A Heterocyclic compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-02-23 US disclosed
US-4713197-A Nitrogen-containing heterocyclic compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-12-15 US disclosed
US-4694098-A WIDE MESOMORPHIC RANGE HITACHI, LTD. (JP) 1987-09-15 US disclosed
EP-0182054-A2 Heterocyclic compounds MERCK PATENT GmbH (DE) 1986-05-28 EP disclosed
EP-0058981-B1 COLORLESS LIQUID CRYSTALLINE COMPOUNDS Hitachi, Ltd. (JP) 1986-01-22 EP disclosed
US-4564694-A CYCLOHEXYL AND PHENYL RING-CONTAINING ALIPHATIC ETHERS HITACHI, LTD. (JP) 1986-01-14 US disclosed
EP-0149238-A2 Nitrogen containing heterocycles MERCK PATENT GmbH (DE) 1985-07-24 EP disclosed
EP-0058981-A2 Colorless liquid crystalline compounds Hitachi, Ltd. (JP) 1982-09-01 EP disclosed
US-4130502-A Liquid crystalline cyclohexane derivatives MERCK PATENT GESELLSCHAFT MIT (DE) 1978-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150337013-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CLPP, CLPTM1, RPN1 CYP2C9 4640/4885MAPT 4574/4885ALDH1A1 4703/4885
US-20140073558-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CLPP, CLPTM1, RPN1 CYP2C9 4640/4885MAPT 4574/4885ALDH1A1 4703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.