Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343683 | 0.91 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL31379766 | 0.79 | MAPT (0.62) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL18872520 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL9124814 | 0.76 | TSHR (0.38) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL9549330 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MAPTCYP3A4GAACYP1A2 | |
| SCHEMBL9124505 | 0.67 | AR (0.39) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL9127906 | 0.65 | ABL1 (0.46) | ALDH1A1MAPTARMAPK1HTR2B | |
| SCHEMBL1921405 | 0.61 | GAA (0.52) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL9513153 | 0.59 | ALDH1A1 (0.91) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL11961726 | 0.59 | ALDH1A1 (0.91) | ALDH1A1MAPTMEN1KMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274135-A | Aminating in the presence of a metal-containing catalyst | THE DOW CHEMICAL COMPANY (US) | 1993-12-28 | — | — | US | disclosed |