SCHEMBL1921405

SCHEMBL1921405

Cc1ccc(Nc2ccc(Nc3ccc(C)c(C)c3)cc2)cc1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
MEN1 O00255 1/20 0.52
G6PD P11413 1/20 0.52
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 4/20 0.52
ALOX15 P16050 2/20 0.52
CYP3A4 P08684 1/20 0.52
THRB P10828 1/20 0.52
RECQL P46063 1/20 0.52
HIF1A Q16665 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MAPT P10636 2/20 0.52
HPGD P15428 2/20 0.52
HSD17B10 Q99714 1/20 0.52
POLB P06746 1/20 0.50
TP53 P04637 1/20 0.50
JAK2 O60674 1/20 0.48
KDM4E B2RXH2 1/20 0.48
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1155655 0.97 ALDH1A1 (0.53) GAAL3MBTL1MEN1G6PDKMT2A
SCHEMBL30508518 0.97 ALDH1A1 (0.53) GAAL3MBTL1MEN1G6PDKMT2A
SCHEMBL31549984 0.97 ALDH1A1 (0.53) GAAL3MBTL1MEN1G6PDKMT2A
SCHEMBL1921952 0.93 ALDH1A1 (0.47) GAAL3MBTL1MEN1G6PDKMT2A
SCHEMBL25994059 0.93 ALDH1A1 (0.47) GAAL3MBTL1MEN1G6PDKMT2A
SCHEMBL7763499 0.93 GAA (0.63) GAAL3MBTL1MEN1G6PDKMT2A
Benzene SCHEMBL7148507 0.92 KMT2A (0.50) GAAL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL4826082 0.91 HPGD (0.60) GAAL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL30542248 0.91 HPGD (0.60) GAAL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL20850476 0.90 ALDH1A1 (0.48) GAAL3MBTL1MEN1G6PDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed