Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | CALML3 | P27482 | 6/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9482302 | 1.00 | GRM2 (0.64) | GRM2MAOAMAOBCALML3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11233573 | 0.86 | GRM2 (0.60) | GRM2MAOAMAOBCALML3F10 | |
| SCHEMBL7297166 | 0.86 | GRM2 (0.63) | GRM2MAOAMAOBCALML3SIGMAR1 | |
| SCHEMBL16809996 | 0.86 | MAOA (0.70) | GRM2MAOAMAOBCALML3SIGMAR1 | |
| SCHEMBL3323919 | 0.86 | MAOA (0.58) | GRM2MAOAMAOBCALML3F10 | |
| SCHEMBL3327082 | 0.86 | MAOA (0.58) | GRM2MAOAMAOBCALML3F10 | |
| SCHEMBL12728919 | 0.86 | MAOA (0.70) | GRM2MAOAMAOBCALML3SIGMAR1 | |
| SCHEMBL412168 | 0.86 | MAOA (0.58) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL7300213 | 0.86 | GRM2 (0.63) | GRM2MAOAMAOBCALML3SIGMAR1 | |
| SCHEMBL16685880 | 0.86 | MAOA (0.58) | GRM2MAOAMAOBCALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235063-A | Acetal derivatives of 3-aryl-2-oxazolidine; antidepressants | DELALANDE S.A. (FR) | 1993-08-10 | — | — | US | disclosed |
| US-5036090-A | Antidepressants | DELALANDE S.A. (FR) | 1991-07-30 | — | — | US | disclosed |