Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | USP8 | P40818 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549529 | 0.81 | CA1 (0.33) | MAPTGAA | |
| SCHEMBL9543115 | 0.75 | MAOB (0.39) | — | |
| SCHEMBL19919277 | 0.68 | PIM1 (0.40) | KMT2APIM1PDK2THRBTDP1 | |
| SCHEMBL9542009 | 0.65 | SMN1; SMN2 (0.40) | KMT2AALDH1A1LMNAMEN1SMN1; SMN2 | |
| SCHEMBL9544341 | 0.65 | ADORA1 (0.36) | KMT2AMAPTKDM4EMEN1GAA | |
| SCHEMBL31426363 | 0.64 | PDK2 (0.39) | KMT2APIM1PDK2THRBTDP1 | |
| SCHEMBL161663 | 0.64 | PDK2 (0.39) | KMT2APIM1PDK2THRBTDP1 | |
| SCHEMBL9549343 | 0.64 | KMT2A (0.49) | KMT2AMAPTLMNAKDM4EMEN1 | |
| SCHEMBL19342868 | 0.64 | PIM1 (0.41) | KMT2APIM1PDK2THRBTDP1 | |
| SCHEMBL24576598 | 0.61 | PDK2 (0.37) | KMT2APIM1PDK2THRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219839-A | Analgesics; anticonvulsant and -epileptic agents; antidepressants; anxiolytic, antiarrhythmic and hypotensive agents; anticoagulants | LABORATORIES UPSA (FR) | 1993-06-15 | — | — | US | disclosed |