Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31426363 | 0.69 | PDK2 (0.39) | PIM1PDK2THRBTDP1APEX1 | |
| SCHEMBL161663 | 0.69 | PDK2 (0.39) | PIM1PDK2THRBTDP1APEX1 | |
| SCHEMBL9549458 | 0.68 | KMT2A (0.44) | PIM1PDK2THRBTDP1KMT2A | |
| SCHEMBL212466 | 0.65 | KMT2A (0.43) | PDK2THRBTDP1KMT2AMAPT | |
| SCHEMBL24576598 | 0.65 | PDK2 (0.37) | PIM1PDK2THRBTDP1KMT2A | |
| SCHEMBL15611287 | 0.64 | APEX1 (0.42) | PDK2THRBTDP1APEX1KMT2A | |
| SCHEMBL1394180 | 0.64 | KMT2A (0.40) | PDK2KMT2A | |
| SCHEMBL29355276 | 0.63 | KMT2A (0.56) | PDK2THRBTDP1APEX1KMT2A | |
| SCHEMBL44942 | 0.63 | KMT2A (0.56) | PDK2THRBTDP1APEX1KMT2A | |
| SCHEMBL1395101 | 0.62 | PDK2 (0.41) | PDK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180057428-A1 | Enhancing thermal stability of bulk heterojunction solar cells with fluorenone derivatives | HONG KONG BAPTIST UNIVERSITY (HK) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057428-A1 | Enhancing thermal stability of bulk heterojunction solar cells with fluorenone derivatives | AXIN2, TRPA1, TCF4 | PIM1 4758/4885PDK2 619/4885THRB 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.