Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 9/20 | 0.45 |
| ▸ | HTR2C | P28335 | 5/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549507 | 0.81 | HTR2A (0.42) | KMT2AHTR2AHTR2CHTR2BMAOB | |
| SCHEMBL11605887 | 0.65 | HTR2A (0.42) | KMT2AHTR2AMAOB | |
| SCHEMBL5398454 | 0.64 | APEX1 (0.47) | KMT2AHTR2AMAOBLMNAKDM4E | |
| SCHEMBL9549458 | 0.64 | KMT2A (0.44) | KMT2ALMNAGAANPSR1KDM4E | |
| SCHEMBL30949491 | 0.61 | KMT2A (0.42) | KMT2AMAOBLMNAKDM4EMEN1 | |
| SCHEMBL17050287 | 0.61 | APEX1 (0.48) | KMT2AHTR2AMAOBLMNAKDM4E | |
| SCHEMBL11268691 | 0.60 | HTR2A (1.00) | KMT2AHTR2AHTR2CHTR2BMAOB | |
| SCHEMBL16601529 | 0.60 | HTR2C (0.55) | HTR2AHTR2CHTR2BMAOBKDM4E | |
| SCHEMBL4325901 | 0.60 | PDK2 (0.56) | KMT2ALMNAKDM4EMEN1MAPT | |
| SCHEMBL30899336 | 0.60 | PDK2 (0.56) | KMT2ALMNAKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219839-A | Analgesics; anticonvulsant and -epileptic agents; antidepressants; anxiolytic, antiarrhythmic and hypotensive agents; anticoagulants | LABORATORIES UPSA (FR) | 1993-06-15 | — | — | US | disclosed |