Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549618 | 0.94 | CYP3A4 (0.46) | SIGMAR1CYP3A4TDP1HRH1HTR2A | |
| SCHEMBL9549561 | 0.86 | CYP3A4 (0.50) | SIGMAR1CYP3A4TDP1HRH1HTR2A | |
| SCHEMBL9549730 | 0.82 | SIGMAR1 (0.50) | SIGMAR1CYP3A4TDP1HRH1HTR2A | |
| SCHEMBL10790182 | 0.82 | CYP3A4 (0.60) | SIGMAR1CYP3A4TDP1HRH1HTR2A | |
| SCHEMBL9549821 | 0.81 | SIGMAR1 (0.47) | SIGMAR1CYP3A4TDP1HRH1HTR2A | |
| SCHEMBL6455349 | 0.79 | CYP3A4 (0.46) | SIGMAR1CYP3A4TDP1HRH1HTR2A | |
| SCHEMBL27885690 | 0.79 | TDP1 (0.50) | SIGMAR1CYP3A4TDP1HRH1HTR2A | |
| Bromide SCHEMBL4352867 | 0.78 | TDP1 (0.44) | SIGMAR1CYP3A4TDP1HRH1HTR2A | |
| Bromide SCHEMBL4353499 | 0.78 | CYP3A4 (0.44) | SIGMAR1CYP3A4TDP1HRH1HTR2A | |
| SCHEMBL2505530 | 0.77 | TSHR (0.52) | CYP3A4TDP1HRH1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208317-A | Molding materials of cured epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5109099-A | ADVANCING EPOXY RESINS IN PRESENCE OF AMINO GROUP-CONTAINING PHOSPHONIUM CATALYST | THE DOW CHEMICAL COMPANY (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0441243-A2 | Precatalyzed catalyst compositions, process for preparing epoxy resins, curable compositions, articles resulting from curing the resultant compositions | THE DOW CHEMICAL COMPANY (US) | 1991-08-14 | — | — | EP | disclosed |
| US-4981926-A | Rapid and selective curing using phosphonium catalyst containing an amine group; polyepoxides | THE DOW CHEMICAL COMPANY (US) | 1991-01-01 | — | — | US | disclosed |