Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549831 | 0.81 | CYP3A4 (0.44) | TDP1CYP3A4ESR1ESR2KCNN4 | |
| SCHEMBL16054303 | 0.75 | TDP1 (0.71) | TDP1CYP3A4ESR1ESR2KCNN4 | |
| 1,2-Dibromoethane SCHEMBL28837174 | 0.75 | TDP1 (0.71) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| N-Propyl Bromide SCHEMBL1400032 | 0.73 | TDP1 (0.60) | TDP1CYP3A4ESR1ESR2KCNN4 | |
| SCHEMBL16055414 | 0.73 | CYP3A4 (0.67) | TDP1CYP3A4ESR1ESR2KCNN4 | |
| Bromoethane SCHEMBL43961 | 0.73 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2KCNN4 | |
| Bromide SCHEMBL31187017 | 0.72 | — | — | |
| Bromide SCHEMBL31187015 | 0.72 | — | — | |
| Dibromomethane SCHEMBL7950072 | 0.72 | TDP1 (0.75) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Dibromomethane SCHEMBL5329477 | 0.72 | TDP1 (0.75) | TDP1CYP3A4ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208317-A | Molding materials of cured epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5109099-A | ADVANCING EPOXY RESINS IN PRESENCE OF AMINO GROUP-CONTAINING PHOSPHONIUM CATALYST | THE DOW CHEMICAL COMPANY (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0441243-A2 | Precatalyzed catalyst compositions, process for preparing epoxy resins, curable compositions, articles resulting from curing the resultant compositions | THE DOW CHEMICAL COMPANY (US) | 1991-08-14 | — | — | EP | disclosed |
| US-4981926-A | Rapid and selective curing using phosphonium catalyst containing an amine group; polyepoxides | THE DOW CHEMICAL COMPANY (US) | 1991-01-01 | — | — | US | disclosed |