Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968721 | 0.88 | MYC (0.49) | ESR1ESR2MYCPOLBALDH1A1 | |
| SCHEMBL31275905 | 0.86 | ESR1 (0.66) | ESR1ESR2MYCPOLBALDH1A1 | |
| SCHEMBL4657709 | 0.82 | MEN1 (0.58) | MYCPOLBALDH1A1MAPTLMNA | |
| SCHEMBL31198543 | 0.82 | MEN1 (0.58) | MYCPOLBALDH1A1MAPTLMNA | |
| SCHEMBL283244 | 0.80 | ESR1 (0.65) | ESR1ESR2POLBALDH1A1MAPT | |
| SCHEMBL29579448 | 0.80 | ESR1 (0.65) | ESR1ESR2POLBALDH1A1MAPT | |
| SCHEMBL29412612 | 0.80 | ESR1 (0.65) | ESR1ESR2POLBALDH1A1MAPT | |
| SCHEMBL31276066 | 0.80 | ESR1 (0.43) | ESR1ESR2MYCPOLBALDH1A1 | |
| SCHEMBL9220275 | 0.78 | HNF4A (0.45) | ESR1ESR2MYCPOLBALDH1A1 | |
| SCHEMBL38651249 | 0.77 | ESR1 (0.62) | ESR1ESR2MYCPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5194338-A | — | — | None | — | — | JP | disclosed |
| JP-H05194338-A | 9,9-BIS@(3754/24)4-AMINOPHENYL)FLUORENECARBOXYLIC ACID | NIPPON STEEL CORP | 1993-08-03 | — | — | JP | disclosed |