Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 13/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549745 | 1.00 | TBXAS1 (0.43) | TBXAS1EPHX2PDE4DGPR52LMNA | |
| SCHEMBL9734751 | 1.00 | TBXAS1 (0.43) | TBXAS1EPHX2PDE4DGPR52LMNA | |
| SCHEMBL9549809 | 0.83 | TBXAS1 (0.60) | TBXAS1 | |
| SCHEMBL10735286 | 0.82 | TBXAS1 (0.61) | TBXAS1EPHX2GPR52LMNA | |
| SCHEMBL10735288 | 0.82 | TBXAS1 (0.61) | TBXAS1EPHX2GPR52LMNA | |
| SCHEMBL9549644 | 0.81 | TBXAS1 (0.44) | TBXAS1EPHX2PDE4DLMNAMAPK1 | |
| SCHEMBL2490139 | 0.81 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL9549815 | 0.81 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL9549576 | 0.79 | TBXAS1 (0.48) | TBXAS1PDE4DLMNA | |
| SCHEMBL3431967 | 0.78 | TBXAS1 (0.44) | TBXAS1EPHX2PDE4DLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229385-A | Thromboxane A2 and lipoxygenase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-20 | — | — | US | disclosed |
| US-4985447-A | USEFUL FOR TREATMENT AND PREVENTION OF DISEASES DUE TO DYSFUNCTION OF HEART, BRAIN, LUNG AND KIDNEY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-01-15 | — | — | US | disclosed |