Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549809 | 0.85 | TBXAS1 (0.60) | TBXAS1 | |
| SCHEMBL2490139 | 0.83 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL9549815 | 0.83 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL17596760 | 0.83 | TBXAS1 (0.60) | TBXAS1EPHX2GRM8GRM4LMNA | |
| SCHEMBL9549644 | 0.81 | TBXAS1 (0.44) | TBXAS1EPHX2LMNAMAPK1PDE4D | |
| SCHEMBL9549576 | 0.79 | TBXAS1 (0.48) | TBXAS1LMNAPDE4DSMN1; SMN2L3MBTL1 | |
| SCHEMBL9734751 | 0.78 | TBXAS1 (0.43) | TBXAS1EPHX2LMNAMAPK1PDE4D | |
| SCHEMBL9549751 | 0.78 | TBXAS1 (0.43) | TBXAS1EPHX2LMNAMAPK1PDE4D | |
| SCHEMBL9549745 | 0.78 | TBXAS1 (0.43) | TBXAS1EPHX2LMNAMAPK1PDE4D | |
| SCHEMBL28296835 | 0.78 | TBXAS1 (0.58) | TBXAS1EPHX2GRM8GRM4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262508-A2 | SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | Edison Pharmaceuticals, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009111576-A2 | 2-SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | EDISON PHARMACEUTICALS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |