Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033202 | 0.83 | IDO1 (0.41) | LMNACYP1A2CYP2C19MAOBAPP | |
| SCHEMBL3631052 | 0.83 | IDO1 (0.41) | MAPTMAOBAPPALDH1A1GAA | |
| SCHEMBL30190420 | 0.83 | ESR1 (0.31) | CYP3A4LMNAALDH1A1CHRM2SLC6A3 | |
| SCHEMBL7421540 | 0.79 | — | — | |
| SCHEMBL27805656 | 0.78 | HDAC3 (0.34) | ALDH1A1RAB9ANPC1KCNH2SMN1; SMN2 | |
| SCHEMBL5368865 | 0.77 | MEN1 (0.30) | MAPTCYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL9549749 | 0.76 | IDO1 (0.49) | MAPTLMNAMAOBALDH1A1RAB9A | |
| SCHEMBL1491341 | 0.75 | TSHR (0.44) | MAPTCYP3A4TSHRMAOBAPP | |
| SCHEMBL8904260 | 0.75 | TDP1 (0.44) | MAPTCYP3A4TSHRLMNACYP1A2 | |
| SCHEMBL8131345 | 0.75 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235063-A | Acetal derivatives of 3-aryl-2-oxazolidine; antidepressants | DELALANDE S.A. (FR) | 1993-08-10 | — | — | US | disclosed |