Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584058 | 0.83 | ACHE (0.37) | TSHRCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5074489 | 0.81 | LTA4H (0.50) | TSHRCYP3A4CYP1A2CYP2C19LMNA | |
| SCHEMBL4872803 | 0.81 | CYP19A1 (0.34) | TSHRCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6585059 | 0.81 | MGLL (0.43) | TDP1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8904259 | 0.81 | CYP2D6 (0.33) | TSHRCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20535808 | 0.81 | APP (0.34) | TSHRCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6987433 | 0.81 | LTA4H (0.46) | TSHRCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8712246 | 0.79 | THRB (0.33) | TSHRCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10046730 | 0.79 | TSHR (0.41) | TDP1TSHRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL3128008 | 0.78 | CYP3A4 (0.30) | CYP3A4CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656264-A | ADMINISTERING TO THE SCALP OF THE MALE A PREPERATION CONSITING OF 6-BENZYLAMINOPURINE | SANSYO SEIYAKU CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0540854-A2 | Preparation for promoting hair growth | Sansho Seiyaku Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |