Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525897 | 0.79 | KDM1A (0.49) | CA12CA2HIF1AMAPTMEN1 | |
| SCHEMBL7897640 | 0.78 | ALDH1A1 (0.50) | CA12CA2CA9TAAR1MAPT | |
| SCHEMBL7421821 | 0.78 | GRIN2D (0.40) | CA12CA2CA9TAAR1MAPT | |
| SCHEMBL13892090 | 0.77 | GRIN2D (0.39) | CA12CA2CA9TAAR1MAPT | |
| SCHEMBL6700720 | 0.77 | GRIN2D (0.39) | CA12CA2CA9TAAR1MAPT | |
| SCHEMBL8029769 | 0.77 | MAPT (0.59) | MAPTMEN1ALDH1A1HTTKMT2A | |
| SCHEMBL2487614 | 0.75 | TRPV1 (0.40) | TAAR1MAPTALDH1A1HTTIDO1 | |
| SCHEMBL28103028 | 0.75 | GAA (0.34) | HSPA5MAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL2002382 | 0.74 | GAA (0.50) | TSHRMAPTALDH1A1HTTKMT2A | |
| SCHEMBL49745 | 0.74 | HSPA5 (1.00) | HSPA5CA12CA2CA9KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5058986-A | — | — | None | — | — | JP | disclosed |
| JP-H0558986-A | SUBSTITUTED OXYBENZYLPHENYLGUANIDINE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL GERMICIDE | HOKKO CHEM IND CO LTD | 1993-03-09 | — | — | JP | disclosed |