SCHEMBL9550277

SCHEMBL9550277

NCC1CN(c2ccc(-c3ccccc3)cc2)C(=O)O1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.60
GRM2 Q14416 13/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5007547 0.91 GRM2 (0.69) F10GRM2
SCHEMBL3798210 0.91 GRM2 (0.69) F10GRM2
SCHEMBL9550251 0.85 MAOA (0.59) GRM2
SCHEMBL14168239 0.84 F10 (0.66) F10GRM2
SCHEMBL18786447 0.82 CALML3 (0.65) F10
SCHEMBL18786420 0.82 CALML3 (0.65) F10
SCHEMBL15203256 0.82 GRM2 (0.64) F10GRM2
SCHEMBL9823520 0.82 F10 (0.63) F10GRM2
SCHEMBL3328770 0.82 F10 (0.63) F10GRM2
SCHEMBL12728922 0.82 GRM2 (0.64) F10GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5254577-A Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-10-19 US disclosed
US-5130316-A Arylbenzene oxazolidinone compounds DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1992-07-14 US disclosed
US-5043443-A Bactericides DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1991-08-27 US disclosed
US-4948801-A Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-14 US disclosed
EP-0352781-A2 Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1990-01-31 EP disclosed