Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660067 | 0.73 | LMNA (0.37) | ALDH1A1HSD17B10MAPTSMN1; SMN2POLB | |
| SCHEMBL5376960 | 0.72 | DAGLA (0.36) | GAAMGLLP2RX4 | |
| SCHEMBL9378936 | 0.69 | LMNA (0.36) | ALDH1A1GAAHSD17B10CYP3A4MAPT | |
| SCHEMBL9491268 | 0.69 | ALDH1A1 (0.40) | ALDH1A1HSD17B10SMN1; SMN2POLBHPGD | |
| SCHEMBL11035938 | 0.68 | MAPT (0.54) | GAAHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9725531 | 0.67 | TDP1 (0.32) | ALDH1A1SMN1; SMN2POLBHPGDMGLL | |
| SCHEMBL7658352 | 0.66 | POLB (0.34) | SMN1; SMN2POLBMGLLLMNAP2RX4 | |
| SCHEMBL9015526 | 0.65 | MAPT (0.33) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL16143757 | 0.65 | USP2 (0.40) | ALDH1A1ALOX15HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL10882291 | 0.65 | LMNA (0.59) | ALDH1A1GAAALOX15HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5194432-A | — | — | None | — | — | JP | disclosed |
| JP-H05194432-A | TRIAZOLE DERIVATIVE AND HERBICIDE | HOKKO CHEM IND CO LTD | 1993-08-03 | — | — | JP | disclosed |