SCHEMBL9550554

SCHEMBL9550554

COCCOCCP(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
ALDH1A1 P00352 3/20 0.37
RAB9A P51151 2/20 0.37
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 1/20 0.37
PKM P14618 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 2/20 0.35
ALOX5 P09917 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
AR P10275 1/20 0.32
HPGD P15428 1/20 0.31
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12313461 1.00 CA2 (0.38) CA2SMN1; SMN2ALDH1A1RAB9AKDM4E
SCHEMBL7167827 0.90 KMT2A (0.38) SMN1; SMN2ALDH1A1RAB9AKDM4EMEN1
SCHEMBL6057042 0.88 CA2 (0.38) CA2ALDH1A1RAB9AMEN1KMT2A
SCHEMBL2227767 0.88 TDP1 (0.39) SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A
Bromide SCHEMBL28416675 0.86 CA2 (0.37) CA2ALDH1A1RAB9AMEN1KMT2A
SCHEMBL15417419 0.80 MAPK1 (0.40) CA2SMN1; SMN2ALDH1A1RAB9AKDM4E
SCHEMBL9550556 0.80 KDM4E (0.37) SMN1; SMN2ALDH1A1RAB9AKDM4ENPC1
SCHEMBL18486539 0.78 MAPK1 (0.39) CA2SMN1; SMN2ALDH1A1RAB9AKDM4E
SCHEMBL18486599 0.77 MAPK1 (0.38) CA2SMN1; SMN2ALDH1A1KDM4ENPC1
SCHEMBL18486723 0.77 MAPK1 (0.38) CA2SMN1; SMN2ALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326286-B1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1993-02-10 EP claimed
EP-0419485-B1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1993-01-20 EP claimed
US-5026886-A Deprotonation of a bis(alkyl-substituted)biaryl compound and reacting the biaryl anion with a Group 5 element compound EASTMAN KODAK COMPANY (US) 1991-06-25 US claimed
EP-0326286-A1 Preparation of bidentate ligands EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-08-02 EP claimed
WO-1989006653-A1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1989-07-27 WO claimed
US-7422836-B2 Dissolution rate modifiers for photoresist compositions PROMERUS LLC (US) 2008-09-09 US disclosed
EP-0326286-B1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1993-02-10 EP disclosed
EP-0419485-B1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1993-01-20 EP disclosed
EP-0451201-A1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1991-10-16 EP disclosed
US-5026886-A Deprotonation of a bis(alkyl-substituted)biaryl compound and reacting the biaryl anion with a Group 5 element compound EASTMAN KODAK COMPANY (US) 1991-06-25 US disclosed
WO-1990006930-A1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1990-06-28 WO disclosed
EP-0326286-A1 Preparation of bidentate ligands EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-08-02 EP disclosed
WO-1989006653-A1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1989-07-27 WO disclosed