SCHEMBL2227767

SCHEMBL2227767

c1ccc(P(CCOCCP(c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
KCNA3 P22001 1/20 0.33
ALDH1A1 P00352 4/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
PTK2B Q14289 1/20 0.31
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPK1 P28482 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7167827 0.98 KMT2A (0.38) TDP1CYP3A4TSHRKMT2AMEN1
SCHEMBL9550554 0.88 CA2 (0.38) TDP1CYP3A4TSHRKMT2AMEN1
SCHEMBL12313461 0.88 CA2 (0.38) TDP1CYP3A4TSHRKMT2AMEN1
SCHEMBL9550556 0.87 KDM4E (0.37) TDP1CYP3A4TSHRKMT2AMEN1
SCHEMBL10581713 0.86 CYP3A4 (0.36) TDP1CYP3A4TSHRKMT2AMEN1
SCHEMBL30480022 0.83 CYP11B1 (0.35) TDP1CYP3A4KMT2ALMNAALDH1A1
Carbon Monoxide SCHEMBL10733903 0.83 LMNA (0.36) TSHRKMT2AMEN1LMNAALDH1A1
Formaldehyde SCHEMBL11358299 0.83 LMNA (0.36) TSHRKMT2AMEN1LMNAALDH1A1
Carbon Monoxide SCHEMBL11358295 0.82 LMNA (0.35) TSHRKMT2AMEN1LMNAALDH1A1
SCHEMBL31081595 0.81 CYP3A4 (0.36) TDP1CYP3A4KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO claimed
EP-2981560-B1 CURING OF LIQUID THERMOSETTING RESINS REICHHOLD LLC 2 (US) 2021-10-13 EP claimed
EP-2981560-A1 CURING OF LIQUID THERMOSETTING RESINS Reichhold, Inc. (US) 2016-02-10 EP claimed
US-9068045-B2 Curing of liquid thermosetting resins REICHHOLD, INC. (US) 2015-06-30 US claimed
WO-2014165425-A1 CURING OF LIQUID THERMOSETTING RESINS REICHHOLD, INC. (US) 2014-10-09 WO claimed
US-20140303315-A1 CURING OF LIQUID THERMOSETTING RESINS Polynt Composites USA Inc. 2014-10-09 US claimed
EP-1598053-B1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres OREAL (FR) 2006-12-20 EP claimed
EP-1598053-A1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres L'OREAL (FR) 2005-11-23 EP claimed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US claimed
EP-0949265-B1 RADIOACTIVE TRANSITION METAL NITRIDE HETERO-COMPLEX NIHON MEDIPHYSICS CO LTD (JP) 2003-05-07 EP claimed
US-20020048549-A1 Radioactive transition metal nitride heterocomplex DUATTI ADRIANO (IT) 2002-04-25 US claimed
EP-0949265-A1 RADIOACTIVE TRANSITION METAL NITRIDE HETERO-COMPLEX Nihon Medi-Physics Co., Ltd. (JP) 1999-10-13 EP claimed
EP-0309056-A1 Process for the hydroformylation of olefins SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-03-29 EP claimed
JP-1113332-A None JP disclosed
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO disclosed
US-20230165771-A1 PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION L'OREAL (FR) 2023-06-01 US disclosed
US-5177253-A Process for the preparation of alpha,beta-olefinically unsaturated compounds SHELL OIL COMPANY (US) 1993-01-05 US disclosed
JP-H01113332-A HYDROFORMYLATING METHOD OF OLEFIN SHELL INTERNATL RES MAATSCHAPPIJ BV 1989-05-02 JP disclosed
EP-0309056-A1 Process for the hydroformylation of olefins SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-03-29 EP disclosed
EP-0309056-A1 Process for the hydroformylation of olefins SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165771-A1 PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION KRT18, CKAP4, VIM TDP1 3775/4885CYP3A4 4371/4885TSHR 4711/4885
US-20020048549-A1 Radioactive transition metal nitride heterocomplex SHBG, GNRHR, PRMT5 TDP1 1924/4885CYP3A4 2456/4885TSHR 46/4885
US-20050251928-A1 Method for stripping artificial color from keratin fibers KRT18, DSG1, JUP TDP1 3996/4885CYP3A4 4442/4885TSHR 4245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.