Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617701 | 1.00 | KDM4E (0.51) | KDM4EABCC9ABCB1SIRT2CYP3A4 | |
| SCHEMBL9529230 | 0.85 | KDM4E (0.54) | KDM4EABCC9ABCB1SIRT2CYP3A4 | |
| SCHEMBL9397668 | 0.80 | KDM4E (0.72) | KDM4EABCC9ABCB1CYP3A4ALOX15 | |
| SCHEMBL9398511 | 0.80 | KDM4E (0.72) | KDM4EABCC9ABCB1CYP3A4ALOX15 | |
| SCHEMBL9398721 | 0.80 | KDM4E (0.72) | KDM4EABCC9ABCB1CYP3A4ALOX15 | |
| SCHEMBL9533264 | 0.79 | SIRT2 (0.57) | KDM4EABCC9ABCB1SIRT2CYP1A2 | |
| SCHEMBL9398457 | 0.78 | KDM4E (0.59) | KDM4EABCC9ABCB1CYP3A4ALOX15 | |
| SCHEMBL9398440 | 0.78 | KDM4E (0.59) | KDM4EABCC9ABCB1CYP3A4ALOX15 | |
| SCHEMBL9398445 | 0.78 | KDM4E (0.59) | KDM4EABCC9ABCB1CYP3A4ALOX15 | |
| SCHEMBL10590412 | 0.77 | ABCC9 (0.39) | KDM4EABCC9CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339562-B1 | BENZOPYRAN COMPOUND AND ITS PHARMACEUTICAL USE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0339562-A1 | Benzopyran compound and its pharmaceutical use | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-11-02 | — | — | EP | disclosed |